Sildenafil 150mg works by inhibiting the enzyme phosphodiesterase type 5 (PDE5), which is responsible for breaking down cyclic guanosine monophosphate (cGMP) in the penile region. When a man is sexually stimulated, nitric oxide (NO) is released, promoting cGMP production, which relaxes the smooth muscles and increases blood flow to the penile. By blocking PDE5, Sildenafil ensures higher cGMP levels, leading to prolonged and sustained erections. The effects last for 4-6 hours, helping men with erectile dysfunction (ED) achieve better performance. It should be taken 30-60 minutes before intercourse and only under medical supervision to ensure safety.
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